Researching the Puzzle
Dr. Lori Bergeron Explores the Effects of Bacteria on Health“Biology
is like a puzzle,” notes Dr. Lori Bergeron, Assistant Professor of
Biology. “I’ve always liked puzzles. No one knows the answers to the
questions that I have proposed. As our research uncovers information, we
start to put the puzzle pieces together. It’s a fascinating process!”
Specializing in microbiology, Dr. Bergeron is currently studying a bacterium known as Actinomyces naeslundii, that thrives on surfaces in the mouth and is a member of a living community referred to as a biofilm. Although A. naeslundii
is not generally thought to be harmful to humans, studies have shown
that the bacteria are part of dental plaque and perhaps contribute to
periodontal disease. Dr. Bergeron’s research is aimed at determining how
genes involved in disease get turned on and off. Recent studies have
shown a connection between poor oral health and cardiovascular disease.
The questions posed by Dr. Bergeron may have implications not only for
dental diseases but for cardiovascular diseases as well.
Students in Dr. Bergeron’s “Genetics” class have also been involved in the research on A. naeslundii.
“I could have given them a ‘canned lab’ with a pre-determined outcome,”
notes Dr. Bergeron. “But science doesn’t work that way. By conducting
research where the answers are not already known, students have to
troubleshoot. That translates into a classroom environment with a direct
correlation to real scientific inquiry.”
The equipment and
materials used to conduct Dr. Bergeron’s research are expensive. Through
the INBRE grant, New England College will make substantial improvements
to the College’s classroom and laboratory facilities allowing students
to conduct more sophisticated research projects. “The enhanced
facilities will have great appeal to students interested in the
biomedical sciences or who are looking to pursue graduate programs in
the sciences,” notes Dr. Bergeron. Laboratory renovations, expected to
be completed for the spring semester, include additional equipment,
cabinets, and workspaces, some of which will meet ADA requirements.
Not
only will the grant allow New England College to upgrade its science
laboratories, student and faculty researchers will also have the
opportunity to use facilities at Dartmouth College and the University of
New Hampshire. Dr. Bergeron has been working closely with Dr. George
O’Toole, Associate Professor of Microbiology and Immunology at Dartmouth
Medical School who specializes in the study of biofilms.
According
to Dr. Bergeron, the INBRE grant awarded by the National Institutes of
Health seeks to encourage research that furthers the knowledge of public
health and that has the potential to benefit society. As she observes,
“The INBRE grant will go a long way in supporting research professionals
to do work that is beyond the call of the classroom. It’s hard to get
money if you don’t already have it. For investigators like us, the INBRE
grant puts us in a better position to apply for additional grants in
the future.”
For more information about the New Hampshire Network of Biomedical
Research Excellence (NH-INBRE), please visit their website at http://nhinbre.org.

